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10.3389/fcvm.2023.1203713 223 ZhangW

Shikonin potentiates therapeutic efficacy of oxaliplatin through reactive oxygen species-mediated intrinsic apoptosis and endoplasmic reticulum stress in oxaliplatin-resistant colorectal cancer cells
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In general, gut microbiota metabolites (SCFAs, Trp, BA) are significant factors influencing IBD, and research is still focused on experimental studies
These results suggest Hcy as an independent NTD factor [104]