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GH induces the generation of insulin-like growth factor 1 (IGF-1, also called somatomedin 1) in the liver and regulates the paracrine production of IGF-1 in many other tissues

The resulting GH pulse is rapid and robust: peak plasma GH concentrations typically occur within 15 to 30 minutes of subcutaneous injection, with the pulse lasting approximately 60 to 90 minutes

However, it should be noted that although parenteral routes can secure nutrient delivery to target tissues, it is always an invasive route and may increase the risk of infections per se

Expression study of mutant cystathionine -synthase found in Japanese patients with homocystinuria

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