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One of these enzymes (glutathione synthetase) requires ATP in order to activate the production of reduced glutathione - this makes glutathione also dependent upon adequate ATP

Satellite cell activation and retention of muscle regenerative potential after long-term denervation

doi: 10.3389/fphar.2025.1639698 Received 02 June 2025 Revised 11 October 2025 Accepted 20 October 2025 Published 21 November 2025 Volume 16 - 2025 Edited by Maria Yelshanskaya, Columbia University, United States Reviewed by Linda Marie Nowak, Cornell University, United States Yue Zeng, Chinese Academy of Sciences (CAS), China Updates Copyright 2025 Garca-Daz, Castellanos, Miguez-Cabello, Picaol, Prez-Gonzlez, Gratacs-Batlle, Vega-Castro, Altafaj, Reyes-Guzmn, Reyes-Montao, Gasull and Soto

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Side effects from IV glutathione are uncommon and mild: temporary flushing, brief metallic taste, or slight discomfort at the injection site
