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Studies have shown that Erastin can also modulate p53 signaling outside its canonical ferroptosis activity, altering transcriptional programs that regulate cell-cycle progression and stress responses and thereby intensifying cytotoxicity in sensitive tissues (96)

Fer-1 fails to enhance the p53/SLC7A11/GPX4 pathway but improves the Nrf2/ferroptosis inhibitory protein 1 pathway, boosting resistance to LPO (You et al., 2023)

doi: 10.3389/fonc.2018.00493

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So this whole crazy dogma of, Dont worry about it, its a tick bite
