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This event, in an inflammatory environment, triggers the breakdown of immune tolerance and activates autoreactive CD4 + T cells that have escaped central and peripheral control mechanisms

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[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Chew E.Y., Clemons T.E., Sangiovanni J.P., Danis R.P., Ferris F.L., Elman M.J., Antoszyk A.N., Ruby A.J., Orth D., Bressler S.B., et al

Seale et al., 2020

Similarly, the simultaneous expression of three or more fluorescent proteins in transgenic mice improved the examination of neural circuitries
