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The concentration of glycosaminoglycans, particularly hyaluronic acid, is up to 10 times higher in CNs than in the surrounding skin [13]

Devlin CM, Leventhal AR, Kuriakose G, Schuchman EH, Williams KJ, Tabas I

During niacin treatment, fasting glucose, insulin and HOMA1-IR (insulin resistance score based on blood glucose and insulin) increased in some individuals up to 1.9-fold after niacin dose of 500 mg, suggesting increased insulin resistance (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Duran-Prado M., Frontinan J., Santiago-Mora R., Peinado J.R., Parrado-Fernandez C., Gomez-Almagro M.V., Moreno M., Lopez-Dominguez J.A., Villalba J.M., Alcain F.J