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The protective effects of rutin on the liver, kidneys, and heart by counteracting organ toxicity caused by synthetic and natural compounds

Combination of astragalus polysaccharide with Diosbulbin B exerts an enhanced antitumor effect in BRAFmut papillary thyroid cancer with decreased liver toxicity

Eur J Clin Pharmacol 80:1137 Yousra M, Elsherbiny NM, El-Shafey M, Said E (2020) The interplay of the inhibitory effect of nifuroxazide on NF-B/STAT3 signaling attenuates acetic acid-induced ulcerative colitis in rats

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This can occur when the bodys immune system reacts to the filler material as a foreign substance, even long after the initial treatment