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The role and mechanism of PKM2 in the development of LPS-induced acute kidney injury

Antioxidants play a key role in mitigating oxidative stress levels in tissues
Briefly, mice were anesthetized using an isoflurane vaporizer (VetEquip, Inc., Livermore, CA) and monitored throughout the procedure for the depth of anesthesia by toe pinch reflex

Figure: Simplified ferroptotic cascade
