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doi: 10.3389/fnut.2022.1040259 Received 09 September 2022 Accepted 09 November 2022 Published 10 January 2023 Volume 9 - 2022 Edited by Domenico Sergi, University of Ferrara, Italy Reviewed by Roberta Masella, National Institutes of Health (ISS), Italy

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A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy

Subcutaneous B12 administration, although promising in select cases such as congenital cobalamin disorders, lacks comprehensive comparative studies against IM and oral routes