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These metabolites have been shown to exert neuroprotective effects by maintaining the integrity of the bloodbrain barrier (BBB), modulating immune responses, and promoting neuronal health (Wang et al., 2018)

The purified protein was run on SDS-PAGE and detected using a coomassie stain

The role of S1PR2 appears highly context-dependent, potentially exerting opposing effects in different tissues or disease states ( In summary, S1PR2 adds another layer of complexity to BA signaling within the TIME, potentially acting as a receptor for conjugated BAs to influence cancer cell invasiveness and inflammation, possibly contributing to a pro-tumorigenic microenvironment in certain settings

Paclitaxel and camptothecin Paclitaxel (PTX) has been approved by the Food and Drug Administration as a radiation sensitizing drug