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3.1.1 Topoisomerase inhibitors Topoisomerase inhibitors are a class of anticancer drugs whose mechanism of action is based on blocking topoisomerase enzymes from re-ligating the DNA strands after supercoiling, thus preventing DNA replication [61]

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[DOI] [PubMed] [Google Scholar] 50.Cadirci E., Altunkaynak B.Z., Halici Z., Odabasoglu F., Uyanik M.H., Gundogdu C., Suleyman H., Halici M., Albayrak M., Unal B