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doi: 10.1002/hem3.59

Hidiroglou M., M
GLS1 expression is regulated by a variety of factors, such as transcription factor c-Myc, transcription factor c-Jun, Sirtuin 5, NF-B, and hypoxia-inducing factor 1 (HIF-1) (Gao et al., 2009

However, addition of OP-1 increased cells sensitivity to IGF-1 and improved cell survival and proteoglycan synthesis, suggesting that the combined therapy is an effective strategy for OA treatment [215]

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Sasabe E., Tatemoto Y., Li D., Yamamoto T., Osaki T
