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Cardiolipin is sequestered by supercomplexes, being protected from degradation, and in turn, stabilises supercomplexes, thus decreasing the electron leakage

A High Capacity cDNA Reverse Transcription Kit (Applied Biosystems, Thermo Fisher Scientific, Waltham, MA, USA) was used to perform the reverse transcription following the manufacturers instructions and using the ProFlex PCR System machine (Applied Biosystems, Thermo Fisher Scientific, Waltham, MA, USA)

Fingolimod is a sphingosine 1-phosphate (S1P) receptor modulator that suppresses the abnormal activity of immune cells (T and B cells) that attack the brains of MS patients

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Under hypoxic settings, the gut modifies its metabolism, frequently transitioning from oxidative phosphorylation to glycolysis 70