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318 Currently, OT-82 is in phase 1 clinical evaluation of safety and efficacy in participants with relapsed or refractory lymphoma (clinicaltrials.gov
FUS interacts with HSP60 to promote mitochondrial damage
Steroids (2018) 133:347
& Sahin, K
After TBI, mitochondrial membrane disruption not only critically impairs oxidative phosphorylation at the site of electron transport but also activates downstream signaling pathways (ROS, caspases, calpains, etc.) that lead to cell death [76]
