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Intentionally or accidentally, about 44,000 to 78,000 Americans end up in the emergency room every year because of Tylenol overdoses

2018 May;15(5):325-40

This pathological NO, and its potent derivative peroxynitrite (ONOO ), inhibit mitochondrial respiratory complexes, contributing to bioenergetic failure or cytopathic hypoxia (45)
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