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Dedicated safety-pharmacology studies covering cardiovascular (including hERG/QT), respiratory, and central-nervous-system function
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Moreover, kynurenine competes with other amino acids, such as methionine and leucine, that are transported by Slc7a5 to T cells, thereby impairing T cell-mediated immune responses [284]

Potential intakes of vitamin E within this range are lower than the UL of 1,000 mg/day advised in the US

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