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Detailed investigations of the mechanism of AMAP toxicity to rat, human, and mouse liver slices are also required

In vivo studies Treatments Erinacines investigated in vivo included erinacine A in nine studies, erinacine S in four studies and erinacine C in two studies

A growing number of studies are utilizing GSH depletion as an effective adjuvant therapy for tumor

In summary, post-translational regulation of GPX4 provides new therapeutic entry points for OA intervention, but the strength of evidence, reproducibility, and clinical relevance of this research still need significant enhancement

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