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The features responsible for the distinct properties of LECs include fenestrations, contractile properties, which propels the fluid through the LVs, and the capability to absorb excess of fluid from the interstitial spaces and transport it back to the bloodstream

In a physical dependence assay (assessed at 6, 14, 42, and 72 hours after the conditioning treatment) shorter pre-convulsive latencies were noted in diazepam conditioned mice than in non-conditioned healthy mice following an isoniazid treatment forty-two and seventy-two hours after the conditioning treatment

Understanding these clinical manifestations is critical for guiding diagnostic strategies, selecting appropriate treatments, and optimizing reproductive outcomes for affected women ( Figure 2 )

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