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10.1016/j.freeradbiomed.2021.11.006 [DOI] [PMC free article] [PubMed] [Google Scholar] Wang H, Wang N, Xu D et al (2020) Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis

This led to the discovery of the short gene regulatory regions called antioxidant response elements (AREs) that are required for xenobiotic and oxidative stress-induced expression of phase II detoxification enzymes (Rushmore and Pickett, 1990