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By modulating oxidative stress and reducing NADPH oxidase-dependent ROS production, luteolin disrupts the redox-sensitive enhancement of fibrotic pathways [19, 115]
Z.DanciuC.RacoviceanuR.et al (2022)
Especially at this time, when we know clearly that sickle RBC are deficient in anti-oxidant capacity, 15 and that oxidative pathways in RBC promote vasoocclusion, 13 understanding the effects of anti-oxidant therapies on sickle RBC biology, the root cause of SCD, should be prioritized
doi: 10.1002/cncr.28001 282 ZhangYTangL-LLiY-QLiuXLiuQMaJ
doi: 10.1053/j.gastro.2008.02.095 98
