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Activated caspase-1 enables the N-terminal sequence of cleaved gasdermin D (GSDMD) to bind to the cell membrane to produce membrane pores, leading to cell pyroptosis and release of a large number of inflammatory factors (152)

doi: 10.1021/np960416j

Effect of vitamin C, hydrocortisone, and thiamine vs hydrocortisone alone on time alive and free of vasopressor support among patients with septic shock: the vitamins randomized clinical trial

Preparation of epigallocatechin gallate decorated Au-Ag nano-heterostructures as NIR-sensitive nano-enzymes for the treatment of osteoarthritis through mitochondrial repair and cartilage protection