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This sexual dimorphism was confirmed in ovine models, with preterm female lambs showing improved respiratory outcomes compared to male subjects (249), although the underlying mechanisms remain elusive

10.1186/s13195-023-01308-4 Alzheimers Res

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Indeed, there is evidence that co-targeting IGF-1R and Src family kinases by combining anti-IGF-1R mAbs/IGF-1R TKIs with dasatinib resulted in more effective growth inhibition than single-agent treatments in rhabdomyosarcoma cell lines [150]

FIGURE 4 The brain-derived neurotrophic factor (BDNF) pathway is considered an important molecular link between GC signaling and LTP regulation