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Environmental health criteria 165

Garcia-Gil FA, Gonzalvo E, Garcia-Garcia JJ, Albendea CD, Guemes A, Tome-Zelaya E, et al

Interestingly, the top-performing analogs in terms of UCHL3 activity all exhibited no UCHL1 inhibition at 500 M, indicating at least 30-fold selectivity for UCHL3

Spatial transcriptomics combined with Slingshot pseudo-time analysis revealed the migration trajectory of VSMC within the vascular wall: VSMC radially migrate from the media to the intima, differentiate into plaque-associated fibrocytes after passing through a myofibrillar intermediate state, and exhibit a spatial trajectory highly correlated with the gene expression gradient of ECM remodeling

[83:21] Brigham Yeah
