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These findings emphasize GCLCs upstream regulatory role and suggest that astrocytic GCLC may be essential in mounting compensatory antioxidant defenses during the early stages of PD

doi: 10.1016/j.jddst.2021.102533 [DOI] [Google Scholar] 84.Masjedi M, Azadi A, Heidari R, Mohammadi-Samani S
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Since tirzepatide is administered once weekly, some patients anecdotally report that morning administration (rather than evening) may help minimize any potential sleep interference, though this has not been formally studied
