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Their results revealed a dosedependent impact, with the 100 mg/kg BW group exhibiting significant ECG alterations, increased heart enzymes (creatine kinaseMB and lactate dehydrogenase), elevated oxidative stress markers (MDA and nitric oxide) and reduced GSH levels, accompanied by histopathological damage to cardiac tissues

Elkins et al., 2006

SOD1 SOD1 is a cytosolic enzyme with relatively uniform activity across different muscle fibers (189, 286)

A total of 5 g His-UBE2m and 5 g GST-PRMT1 were added into a standard 50-L reaction mixture containing 5 l S-adenosyl-l-methionine (SAM, Amersham Bioscience), 50 mM Tris-HCl (pH 8.0), 20 mM KCl, 5 mM DTT, and 4 mM EDTA