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However, once the animal model is established, it is necessary to select indicators to judge and evaluate whether the plateau animal model is successful given that it is impossible to quantify the symptoms of animals based on human standards

In Atlantic salmon, dietary L-carnitine supplementation increased the amino acid concentration in plasma and the liver, especially the three branched-chain amino acids, including leucine, isoleucine, and valine, and increased the protein synthesis capacity, accompanied by the accumulation of protein in organs 52

Noteworthy, TMAO and its precursors are natural components of fish and fish-intake was found to increase TMAO levels in humans [15, 19]

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