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Reactive astrocytes as treatment targets in Alzheimers diseasesystematic review of studies using the APPswePS1dE9 mouse model

ROS-induced OS causes alterations in different organ systems, which are explained as follows: ROS-induced neurotoxicity causes modulation in the neurons such as permeabilization of the cellular membrane, a decrease in the excitability property of neuronal membrane and the activation of the KATP pump (Figure 3)

represents QUEs promoting effect

Several plausible mechanisms have been proposed to understand the role of OS in causing BPH

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