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To maximize the number of cases in the dysplastic BE group, we included all consecutive cases recorded as LGD or HGD in BE from our histopathology database over the preceding five years at the start of our study

Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study
The approach utilized sample enrichment by C18 SPE followed by further enrichment of urinary peptides using a commercially available ProteoSpin kit (Norgen Biotek Corp.)

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