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Without enough B12, people can face nerve pain and peripheral neuropathy
However, critically, as research on transcytosis efficiency has progressed, nanoparticles with smaller diameters ( 200 nm exhibit reduced permeability across the BBB (Hersh et al., 2022)

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Risk is almost always a product of self-sourcing unregulated vials , poor reconstitution , non-sterile technique , or wrong dose for goal - all of which we see in patients who come to us after online DIY protocols
