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Several of these miRNAs target mRNAs encoding AR, AR splice variants or components of the AR protein interactome [109, 110]
Recent studies have reported that hyperandrogenemia induces disorders of glucose and lipid metabolism at the central and peripheral levels, promoting the development and progression of obesity and type 2 diabetes in both female individuals and rodents with PCOS (40, 41)
: Effects of acetyl-L-carnitine in Alzheimer's disease patients unresponsive to acetylcholinesterase inhibitors A Bianchetti et al
TCA, Tricarboxylic acid cycle
10.1096/fj.08-127985 FASEB J
