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Characterization of the structural and functional changes in the myocardium following focal ischemia-reperfusion injury

Kopetz S , Tabernero J, Rosenberg R, Jiang ZQ, Moreno V, Bachleitner-Hofmann T, Lanza G, Stork-Sloots L, Maru D, Simon I, Capell G, Salazar R

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Epigenetic change Epigenetic modifications include DNA methylation, histone modification, chromatin remodeling, and post-translational modification of microrRNA, without involving changes in DNA sequence (Ding et al

Interestingly, in a contrast-induced nephropathy (CIN) model, type 1 diabetic rats received intravenous injection of iopromide, heme inhibited ferroptosis by activating HO-1/Nrf2 and upregulating GPX4