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Two of these proteins, interleukin 12 (IL-12) and interleukin 23 (IL-23), have been implicated as important contributors to the chronic inflammation that is a main feature of ulcerative colitis

Peptide therapy involves the delivery of bioactive peptides that work at the cellular level to promote healing, regeneration, and optimal function

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10.1021/JF8039089 [DOI] [PubMed] [Google Scholar] Kozarski M., Klaus A., Jakovljevic D., Todorovic N., Vunduk J., Petrovi P., et al

Additionally, busulfan has been shown to accelerate the senescence process in murine bone marrow cells, thereby inhibiting their hematopoietic functions [68]