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[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Dikalova A.E., Pandey A., Xiao L., Arslanbaeva L., Sidorova T., Lopez M.G., Billings F.T., Verdin E., Auwerx J., Harrison D.G., et al

Lactylation, is an emerging post-translational modification that adds lactyl groups to both histone and non-histone proteins, participating in a variety of pathophysiological processes

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This could be due to a derepressed transcription of the IGF-1R gene as well as a decreased ubiquitination and degradation of the receptor