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Description
The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells

Alzheimer's disease

Though most NF-B dimer combinations result in the regulation of similar sets of genes, the ability to interact in various homo- and hetero- dimer configurations contributes to their ability to bind with varying affinities to B sites in distinct DNA sequences, and they thus regulate unique, as well as overlapping, gene sets

Cell 182 , 12711283 (2020)

90 The NOX-dependent pathway is the predominant mechanism involved in the production of NETs