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2006 PMID 16609979)
The cost of a new vial is always less than the cost of a compromised protocol that delivers inconsistent or zero results over weeks
Results from the Irbesartan Type 2 Diabetic Nephrology Trial (IDNT) showed a 20% relative risk reduction with irbesartan treatment compared to placebo, but even after that 20% reduction, still 40% of the irbesartan-treated patients saw a doubling of SCr levels and 50% experienced ESRD or death after only four years (24)
It typically peaks at 24 to 48 hours and resolves over 3 to 7 days
Can niacin be combined with other therapeutic agents, such as direct agonists at LXRs, for a more efficacious outcome
