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Astrogliosis is prevalent in the epilepsies, and interestingly a mouse forebrain neuron-specific knockout of SOD2 resulted in seizures, oxidative stress, and marked GFAP and vimentin gene upregulation, indicative of astrogliosis resulting from increased neuronal mtROS (Mndez-Armenta et al., 2014

Photosyn Res
[DOI] [PMC free article] [PubMed] [Google Scholar] 94

Yu Y, Yan Y, Niu F et al (2021) Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases

& Malik, R
