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Description
It plays a crucial role in brain function and the production of DNA and red blood cells

This study used the NNMTi 5-amino-1-methylquinolinium (5A-M1Q), since our lab has set precedence using this probe molecule for proof-of-concept studies 8

Causes of B12 deficiency include: Aging
Daily NNMT inhibitor effects on body weight measures in DIO mice was analyzed using a repeated measures two-way ANOVA with Sidaks multiple comparison posthoc test

Research Mechanism (Mechanism of Action) NNMT normally catalyses the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide (1-MNA)