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10.1016/j.biomaterials.2010.08.077 CrossRef Google Scholar View reference in article 63 KimM.MaengJ.JungJ.KimH

Adding 3mL to a 5mg vial when you meant to add 2mL creates a 1.67mg/mL concentration instead of 2.5mg/mL

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The mechanisms driving central sensitization include elevated substance P, reduced descending pain inhibition, altered glutamate signaling, and microglial activation in the central nervous system

It's also not clear how one dose will perform against different coronavirus strains that are becoming more widespread, including separate strains that were first reported in the U.K., South Africa and Brazil