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A second hypothesis proposed to explain the role of dysbiosis in the pathogenesis of PCOS suggested that hyperandrogenism can induce an alteration of the gut microbiome due to a direct effect of testosterone as a substrate of gut enzyme and an indirect effect via androgen receptors and immune modulation, independent of diet and obesity [95]

2.6 H&E staining procedure for sections of mouse ovarian tissue Mouse ovarian and uterine tissues were fixed in 4% paraformaldehyde for 24 h, dehydrated, and embedded in paraffin

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The boxes which my patients brought in varied in sizes and printing, suggesting that these boxes came from various sources rather than a single manufacturer

[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Amawi H., Ashby C.R., Samuel T., Peraman R., Tiwari A.K