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Specifically, lactate mitigates inflammation by inhibiting TLR4-mediated signaling via GPR81, thereby facilitating the polarization of M2 macrophages and diminishing LPS-induced NF-B activation (154158) Additionally, lactate influences immune cell migration and cytokine production through its export via the monocarboxylate transporter MCT4
B., Grimwood, K., Mulholland, E
An evolutionary perspective on glutathione transferases inferred from class theta glutathione transferase cDNA
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