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2014;9:e91134

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Similarly, nicotinamide riboside given at rest onset (ZT12) doubled cognitive recovery in rats by synchronizing with peak SIRT1 activity and mitochondrial biogenesis rhythms [280], while time-restricted feeding (7:0015:00) improved motor recovery by 37% in aged mice through coordinated hepatic ketogenesis and -oxidation [281]

Acid Extraction of Histones Acid extraction on isolated nuclei was performed as previously described 4
