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Multiple investigations have demonstrated a negative correlation between the activity of GPX3 and the development of carotid atherosclerotic plaques, suggesting that diminished GPX3 activity could serve as an autonomous prognostic indicator for carotid atherosclerosis in individuals with type 2 diabetes mellitus (T2DM) [145,146]

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These compounds work through different mechanisms than Retatrutide and do not directly affect body composition, making them complementary rather than redundant additions

Cell 173, 130139.e10