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The level of histone -hydroxybutyrylation is similar to the level of the more well studied epigenetic histone modification, acetylation
Co-administration increases peak GH and IGF-1 levels in rodent models while maintaining pulsatile patterns
Kim V, Crapo J, Zhao H, et al
J Pharmacol Sci 130(1):1523
Mice subjected to 6 weeks of prolonged stress followed by 6 weeks of social isolation exhibit symptoms of depression, accompanied by elevated levels of astrocyte activation in the dorsal and ventral dentate gyrus regions of the hippocampus (Woodward et al., 2018)
