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2015 Eirini Lionaki, Christina Ploumi, Nektarios Tavernarakis

Riboflavin status in acute ischaemic stroke

Cytoplasmic delivery of siRNA using human-derived membrane penetration-enhancing peptide

More precisely, the complex bearing the most lipophilic benzoate ligand, 3P , showed the highest in vitro antiproliferative activity (mean IC 50 equal to 2.6 M), whereas the complexes with a more hydrophilic carboxylate, such as succinate and acetate, 4P and 5P , were endowed with a lower cytotoxic activity (mean IC 50 of 30.4 and 11.1 M, respectively)

Specifically, simulations suggest that blood Cys and GSH are reduced by 68.7% and 74.1% respectively, whereas cytosolic Cys and GSH are reduced by 81.2% and 64.6% respectively