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For example, low-dose bortezomib induces autophagy and reduces mutant huntingtin aggregation in HD models

LptA and LPS Transport

Gwinn, D

However, inhibition of GLS activity can reduce ATP and GSH levels produced by cardiomyocytes under oxidative stress conditions

Very high values IGF-1 were associated with a better prognosis of ALS suggesting that functions related to IGF-1 could be involved in survival