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Bystander killing effect of DS 8201a, a novel antihuman epidermal growth factor receptor 2 antibodydrug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity

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Qi, L., van Dam, R

Enzymes from the TET and JMJ family catalyse histone and DNA demethylation and they are inhibited by the accumulation succinate, the by-product of these enzymes
Their KAR 1 binding abilities were determined using isothermal titration calorimetry (ITC) assays (Fig
