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CB-839 (Telaglenastat), a potent, reversible, and selective small-molecule inhibitor that targets GLS-1 and has a half-maximal inhibitory concentration (IC 50 ) of 24 nM for recombinant human glutaminase C, has been investigated in solid tumors and in AML, diffuse large B-cell lymphoma, and multiple myeloma cells alone or in combination with other anticancer drugs (10, 11, 2026)

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Acknowledgements The authors of this work were supported financially by the Research Grants Council of Hong Hong and Tam Sai Kit Endowment Fund (Y.-C.H and K.D.K.L) and by the European Community (FP7,2007-2013) under grant agreement no

Pyridoxine: Pyridoxine, also known as vitamin B6, is an essential nutrient that plays a vital role in various biochemical processes in the body

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