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240 It has also been shown that MTA accumulation and secretion occur in MTAP-deficient GBM, but no significant MTA accumulation was detected in vivo because the stromal cells in the TME express WTAP and consume the MTA emitted by tumor cells and increase the activity of PRMT5

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10.1136/bmjopen-2019-033687 [DOI] [PMC free article] [PubMed] 11.Gramer G, Hoffmann GF (2020) Vitamin B12 deficiency in newborns and their mothersnovel approaches to early detection, treatment and prevention of a global health issue

As described above, GSTM2 modulated the size of LDs