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H., & Edden, R

Bedard MC, Chihanga T, Carlile A, Jackson R, Brusadelli MG, Lee D, VonHandorf A, Rochman M, Dexheimer PJ, Chalmers J, Nuovo G, Lehn M, Williams DEJ , Kulkarni A, Carey M, Jackson A, Billingsley C, Tang A, Zender C, Patil Y, Wise-Draper TM, Herzog TJ, Ferris RL, Kendler A, Aronow BJ, Kofron M, Rothenberg ME, Weirauch MT, Van Doorslaer K, Wikenheiser-Brokamp KA, Lambert PF, Adam M, Steven Potter S, Wells SI

This report shows a path towards large-scale production of exosomes, a major issue for broad therapeutic application, using a 3D cell culture bioprocessing method

Several reporters have been devised to enhance signal amplification alongside enzymes, such as polyHRP, fluorophores, functionalized magnetic beads, and upconverting luminous nanoparticles [[127], [128], [129]]