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No build-up of tolerance (loss of biological sensitivity to the compound) has been reported from repeated or continued use from huperzine A, at least according to one early study [38]
Peripheral neuropathy may take 36 months to improve, and some patients experience incomplete recovery, particularly if treatment was delayed
10.1016/j.phymed.2024.155419 117 LuH.LiuF.ZhuQ.ZhangM.LiT.ChenJ.et al (2017)
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